Metastatic amelanotic nodular melanoma during pregnancy

Amelanotic metastatic cutaneous melanoma*

Dermatoscopy of melanocytic lesions has guided the decision of when or not to biopsy a lesion. The use of this tool has increased clinical examination's sensitivity and specificity in 89% and 96% respectively. However, dermatoscopic evaluation of amelanotic or hypomelanotic melanomas, as well as metastases, can be difficult. There is still no standardization for the analysis of these pathologie...

Nodular Melanoma

Metastatic amelanotic melanoma of the jejunum diagnosed on capsule endoscopy.

Address correspondence to: Dr. Omair Atiq, 2055 East South Blvd, Suite 202, Montgomery, AL 36116; Tel: 224-538-1235; E-mail: [email protected] Gastrointestinal (GI) metastasis of malignant melanomas from known primary tumors is a common autopsy finding (50–60%). However, early detection of small bowel melanomas remains a challenge for both radiologists and clinicians. Capsule endoscopy (CE) m...

A rare case of intracranial metastatic amelanotic melanoma with cyst.

A rare case of intracranial metastatic amelanotic melanoma with cyst is presented. The patient was a 51 year old woman with a malignant melanoma arising on her right chest. Two years after a wide excision, skin and brain metastasis occurred. Brain magnetic resonance images demonstrated a tumour with a cyst in the left occipital lobe. Because the tumour showed low intensity on T1 weighted images...

Treatment of metastatic malignant melanoma with vemurafenib during pregnancy.

Introduction The prognosis of stage IV malignant melanoma (MM) has for decades remained poor with median survival of 6 to 9 months. Half of MM tumors carry an activating mutation of the proto-oncogene, B-RAF. The BRAF-inhibitor vemurafenib increases overall and progression-free survival compared with treatment with the chemotherapeutic agent dacarbazine in MM patients with advanced disease. Vem...